Atovaquone and Proguanil 250mg/100mg Single Tablet (Malarone generic tablets)

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Atovaquone/Proguanil 250mg/100mg tablets, also known as generic malarone are an unbranded alternative to the branded malaria tablet Malarone. Ideal for Adults and Children (weighing over 40kg) to prevent malaria when travelling to high risk countries.

What does this medicine do?

Atovaquone/Proguanil, more commonly known as generic Malarone is an anti-malaria drug that will help prevent malaria infection in patients who are travelling to areas of the world where malaria is a problem.
Typically this includes South America, parts of Asia and sub-Saharan Africa.
This medicine is one of the most effective antimalarials available, but no anti-malaria medicine is 100% effective, and so you should avoid insect bites by using an appropriate insect repellent.

How many should I order for my trip?

First of all check this product is suitable for where you are travelling. We recommend NHS FitForTravel. If it is suitable, then to help you work out how many you need we have created a simple malarone tablet calculator. Simply input the number of adults and children over 40kg, how many days you are in the malaria risk country and the number of spare tablets you have (if any) and click calculate. Then let our easy generic Malarone tablet calculator do the rest.

Once you know how many tablets you need, simply increase the quantity on this product page to the calculated amount and click "free online consultation".

How do I take generic Malarone?

Generic Malarone tablets should be taken with or after food as follows:

How often should tablets be taken?1 tablet daily when in the risk area.
When should I start treatment?2 days before entering the risk area.
How often when leaving risk area? 7 days when leaving the risk area.

Please note: If you develop flu like symptoms whilst away or within 1 year of return please see a doctor immediately and explain where you have been.

Who can't take generic Malarone

This medicine should not be used by patients who:

  • Are allergic to atovaquone or proguanil
  • Are pregnant or breastfeeding or intend to be during your trip or two months after, without first seeking specialist advice
  • Have been diagnosed with liver disease or severe kidney disease
  • Have epilepsy or seizures
  • Are currently taking:
    • Warfarin, unless specialist advice has been issued
    • metoclopramide, used to treat nausea and vomiting
    • the antibiotics, tetracycline, rifampicin, or rifabutin
    • efavirenz or certain highly active protease-inhibitors used to treat HIV
    • etoposide used to treat cancer
  • Weigh less than 40kg. You will need to take Malarone Paediatric

Are there any side effects?

Generic Malarone tablets, atovaquone and proguanil are generally well tolerated and users will typically suffer very few side effects, but side effects that are classed as very common, affceting approx 1 in 10 patients include the following:

  • upset stomach
  • diarrhoea
  • headaches

This list of side effects for generic Malarone is not exhaustive and for further information, you should read the patient information leaflet.

Generic Malarone tablets contain: Atovaquone 250mg and Proguanil 100mg

I'm pregnant, can i still take Malaria tablets?

If this is the case we would initially recommend that you do not travel. Malaria can be very dangerous for women who are pregnant. If travel is not avoidable then please give Travelpharm a call for further information. There are usually things we can do to help.

Always read the patient information leaflet before using this product and if you have any questions please speak with a pharmacist or another medical professional.

My doctor has already written me a prescription for Malarone

If you want to send the prescription to us in the post then please increase the quantity box to the amount shown on your prescription and click "I Have a Prescription". You will need to post the original prescription to us before we can ship your order. To speed things up you could use our online consultation option.

Please note that doctors often write prescriptions for the brand Malarone. Whilst Malarone and Atovaquone/Proguanil contain the same active ingredients, Malarone is a brand. Unfortunately, UK law prevents a pharmacy from substituting an unbranded product where a brand has been specified by the prescriber. So if your prescriptions state Malarone you will need to buy Malarone, get the prescription changed or simply fill out our online consultation and let our specialist write your prescription.

Information Reviewed by Andrew Walton MPharm our Superintendent Pharmacist on: 06/11/20

* We don't sell food to non-UK addresses
** Includes N.Ireland, Scottish Highlands, UK Offshore Islands, Isle of Man, Scilly Isles


UK, Channel Islands, N Ireland, Highlands and Islands - Standard delivery arrives 2-3 days after dispatch or for heavy parcels Courier next day after dispatch Mon-Thu.
Europe - We no longer send orders to European or International destinations.


Express delivery arrives 1-2 days after dispatch or for heavy parcels Courier 1-2 days after dispatch Mon-Thu.


Light parcels, delivered Tue-Fri, signature required or for heavy parcels Courier next day Mon-Thu delivery after dispatch.


We understand that you may want, at times, to return an item you’ve purchased from us. To make this process quick and convenient for you, please read the policy below.


We regret that we cannot, by law, accept returns of any medication. If you return a medicine to us all we can do is dispose of it correctly for you as it cannot be resold.

Of course, if we have made a mistake or the product is faulty or damaged, we will accept returns as long as you contact us within 10 days of receiving the order and received the product back within 30 days. Once we have received the returned item  we will refund the amount paid or resend the product.


If for whatever reason you are not satisfied with any other item you have purchased from us, you may return it if you notify us within 10 days of receiving the order and we receive the product back within 30 days. Once we have received the returned item we will refund the amount paid or resend the product.


All returned products must be in their original packaging, unopened and in a re-saleable condition. We only accept returns for products that have been purchased through us.

Any return which does not meet the conditions set above will not be refunded or replaced.

Customer errors: Customers are humans and make mistakes. Sometimes customers put the wrong address in on their order. We are happy to re-ship the item when it is returned to us by Royal Mail. This may take upto 28 days depending on the error made.

Non-Delivery: If an item remains undelivered within 7 working days (exc Sat-Sun) from dispatch then the customer needs to check with their local delivery office/post office for uncollected items.

For further information on returns or to request a refund/return, please contact us.

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